Ulipristal
Search more drugs→What is Ulipristal?
Ulipristal is a medication used primarily for emergency contraception and the treatment of uterine fibroids. It is available under brand names such as Ella and Esmya. The generic name is ulipristal acetate, and it is pronounced as yoo-li-PRIS-tal. Ulipristal belongs to the drug class known as selective progesterone receptor modulators (SPRMs). It is available by prescription and can be administered orally in tablet form.
What conditions or symptoms is Ulipristal used to treat?
Ulipristal is primarily used to prevent pregnancy after unprotected intercourse or contraceptive failure. It is also used in the management of uterine fibroids to reduce symptoms such as heavy menstrual bleeding and pelvic pain. You are having these symptoms, please check them here:Check your heavy bleeding, pelvic pain, or menstrual irregularities symptoms here.
How does Ulipristal work in the body?
Ulipristal works by modulating the progesterone receptor, which plays a crucial role in the menstrual cycle and pregnancy. By binding to these receptors, it alters the endometrial lining and inhibits ovulation, thereby preventing pregnancy. In the case of uterine fibroids, it reduces fibroid size and alleviates associated symptoms by altering the hormonal environment.
In what forms is Ulipristal available?
Ulipristal is available in the form of oral tablets. For emergency contraception, it is typically available as a single 30 mg tablet. For the treatment of uterine fibroids, it is available in a 5 mg tablet form, usually taken daily for a specified duration as prescribed by a healthcare provider.
What are the most common side effects of Ulipristal?
The most common side effects of Ulipristal include headache, nausea, abdominal pain, and dizziness. Some individuals may also experience fatigue and menstrual changes such as spotting or irregular periods. These side effects are generally mild and tend to resolve on their own.
What are the serious or severe side effects of Ulipristal?
Serious side effects of Ulipristal are rare but can include severe allergic reactions, liver dysfunction, and significant changes in menstrual bleeding patterns. If you experience symptoms such as jaundice, severe abdominal pain, or heavy prolonged bleeding, it is important to seek medical attention immediately.
How should Ulipristal be stored safely?
Ulipristal should be stored at room temperature, away from moisture and heat. It should be kept in its original packaging until ready for use to protect it from light. Ensure that it is stored out of reach of children and pets to prevent accidental ingestion.
What are the overall side effects of Ulipristal?
Overall, Ulipristal can cause both common and serious side effects. Common side effects include headache, nausea, and dizziness, while serious side effects may involve liver issues and severe allergic reactions. It is important to monitor for any unusual symptoms and consult a healthcare provider if they occur.
What warnings or precautions should be considered when taking Ulipristal?
Before taking Ulipristal, it is important to inform your healthcare provider of any existing medical conditions, especially liver disease or a history of allergic reactions. Ulipristal should not be used during pregnancy, and breastfeeding women should consult their doctor before use. It is also important to avoid using Ulipristal as a regular contraceptive method.
Who should avoid using Ulipristal?
Individuals who are pregnant or suspect they may be pregnant should avoid using Ulipristal. It is also contraindicated in those with known hypersensitivity to the drug or its components. Patients with severe liver impairment should not use Ulipristal without consulting a healthcare provider.
What important information should I know before using Ulipristal?
It is crucial to understand that Ulipristal is not intended for routine contraceptive use and should only be used as directed by a healthcare provider. It does not protect against sexually transmitted infections. Inform your doctor of all medications you are taking, as Ulipristal can interact with other drugs.
What should I discuss with my healthcare provider before starting Ulipristal?
Discuss your complete medical history with your healthcare provider, including any allergies, liver conditions, or current medications. It is also important to discuss your plans for pregnancy and any concerns about side effects or drug interactions. Your provider can help determine if Ulipristal is the right choice for you.
Does Ulipristal interact with any foods or beverages?
While there are no specific food or beverage restrictions with Ulipristal, it is always advisable to take it with a full glass of water. Avoid consuming grapefruit or grapefruit juice, as it may affect the metabolism of the drug. Always consult your healthcare provider for personalized advice.
Does Ulipristal have interactions with other medications?
Ulipristal can interact with several medications, including those that induce liver enzymes such as rifampin, phenytoin, and carbamazepine. These interactions can reduce the effectiveness of Ulipristal. Always inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.
What should I do if I accidentally take too much Ulipristal?
If you suspect an overdose of Ulipristal, seek immediate medical attention. Symptoms of overdose may include severe nausea, vomiting, or dizziness. It is important to provide healthcare professionals with information about the amount taken and the time of ingestion for appropriate management.
What should I do if I miss a dose of Ulipristal?
Since Ulipristal is typically used as a single-dose medication for emergency contraception, missing a dose is unlikely. However, if you are on a prescribed regimen for uterine fibroids and miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and resume your regular schedule.
What signs or symptoms should I watch for while taking Ulipristal?
While taking Ulipristal, monitor for signs of allergic reactions such as rash, itching, or swelling. Be alert for symptoms of liver issues, including yellowing of the skin or eyes and dark urine. If you experience severe abdominal pain or heavy bleeding, contact your healthcare provider promptly.
When was Ulipristal first developed and approved by the FDA?
Ulipristal was first developed in the early 2000s and gained approval from the European Medicines Agency in 2009 for use in emergency contraception. The U.S. Food and Drug Administration (FDA) approved Ulipristal for emergency contraception in 2010 under the brand name Ella. Its approval for the treatment of uterine fibroids followed in subsequent years.