Kynmobi

What is Kynmobi?

Kynmobi, known generically as apomorphine, is a medication used primarily in the treatment of Parkinson's disease. It is pronounced as "kin-MO-bee" and belongs to the drug class of dopamine agonists. Kynmobi is available by prescription and is administered sublingually, meaning it is placed under the tongue for absorption.

What conditions or symptoms is Kynmobi used to treat?

Kynmobi is primarily used to manage the symptoms of Parkinson's disease, particularly the "off" episodes characterized by muscle stiffness, loss of muscle control, and difficulty moving. If you are experiencing these symptoms, please check them here:Check your muscle stiffness, loss of muscle control, or difficulty moving symptoms here.

How does Kynmobi work in the body?

Kynmobi works by stimulating dopamine receptors in the brain, mimicking the effects of dopamine, a neurotransmitter that is typically deficient in individuals with Parkinson's disease. This action helps to improve movement and reduce the symptoms of "off" episodes, providing relief from the rigidity and tremors associated with the condition.

In what forms is Kynmobi available?

Kynmobi is available in the form of sublingual film, which is designed to dissolve under the tongue for rapid absorption into the bloodstream. This form allows for quick onset of action, making it effective in managing sudden "off" episodes in Parkinson's disease.

What are the most common side effects of Kynmobi?

• Nausea
• Dizziness
• Somnolence (drowsiness)
• Headache
• Yawning

What are the serious or severe side effects of Kynmobi?

• Severe hypotension (low blood pressure)
• Syncope (fainting)
• Hallucinations
• Severe allergic reactions
• Impulse control disorders

How should Kynmobi be stored safely?

Kynmobi should be stored at room temperature, away from moisture and heat. It is important to keep the medication in its original packaging until it is ready to be used. Ensure that it is kept out of reach of children and pets to prevent accidental ingestion.

What are the overall side effects of Kynmobi?

The side effects of Kynmobi can range from mild to severe. Common side effects include nausea, dizziness, and headache, while more serious side effects may involve severe hypotension, hallucinations, and allergic reactions. Patients should be monitored closely for any adverse effects and report them to their healthcare provider promptly.

What warnings or precautions should be considered when taking Kynmobi?

Patients taking Kynmobi should be aware of the potential for severe hypotension and syncope, particularly when standing up quickly. It is crucial to rise slowly from a sitting or lying position to prevent dizziness and fainting. Additionally, patients should be monitored for signs of impulse control disorders and hallucinations.

Who should avoid using Kynmobi?

Individuals with known hypersensitivity to apomorphine or any of its components should avoid using Kynmobi. It is also contraindicated in patients taking certain antiemetic drugs such as ondansetron due to the risk of severe hypotension. Patients with severe cardiovascular conditions should consult their healthcare provider before use.

What important information should I know before using Kynmobi?

Before using Kynmobi, it is important to inform your healthcare provider of any other medications you are taking, as well as any pre-existing health conditions. Understanding the potential side effects and interactions with other drugs is crucial for safe use. Patients should also be aware of the proper administration technique for sublingual films.

What should I discuss with my healthcare provider before starting Kynmobi?

Discuss any history of cardiovascular issues, mental health conditions, or allergies with your healthcare provider before starting Kynmobi. It is also important to review all current medications, including over-the-counter drugs and supplements, to avoid potential interactions. Your healthcare provider can help determine if Kynmobi is the right treatment for you.

Does Kynmobi interact with any foods or beverages?

While Kynmobi does not have specific food interactions, it is advisable to avoid alcohol while taking this medication, as it can exacerbate side effects such as dizziness and drowsiness. Patients should also be cautious with other central nervous system depressants, which can enhance the sedative effects of Kynmobi.

Does Kynmobi have interactions with other medications?

Kynmobi can interact with several medications, including certain antiemetics, antihypertensives, and other dopamine agonists. These interactions can lead to increased side effects or reduced efficacy of the medications. It is important to provide your healthcare provider with a complete list of all medications you are taking to avoid potential interactions.

What should I do if I accidentally take too much Kynmobi?

If you suspect an overdose of Kynmobi, seek immediate medical attention. Symptoms of overdose may include severe nausea, vomiting, dizziness, or fainting. It is important to have emergency contact information readily available and to inform healthcare professionals about the dosage taken.

What should I do if I miss a dose of Kynmobi?

If you miss a dose of Kynmobi, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses to make up for a missed one, as this can increase the risk of side effects.

What signs or symptoms should I watch for while taking Kynmobi?

While taking Kynmobi, monitor for signs of severe side effects such as extreme dizziness, fainting, or hallucinations. Additionally, be aware of any changes in behavior, such as increased impulsivity or unusual urges. Report any concerning symptoms to your healthcare provider promptly for evaluation and management.

When was Kynmobi first developed and approved by the FDA?

Kynmobi was developed as a sublingual film formulation of apomorphine and was approved by the U.S. Food and Drug Administration (FDA) in May 2020. This approval provided a new option for patients with Parkinson's disease to manage their "off" episodes more effectively and conveniently.